Tucked away behind the rustic wood and skateâcrate panelling of Cane & Grain (49â51 Thomas St), Science & Industry is Manchesterâs bestâkept cocktail secret. Youâll find it beyond a hidden door, ascending a staircase to an intimate, opulent lounge filled with leather booths, warm pendant lighting, and elegant beeâthemed wallpaper. This bar doubles as a drinks laboratory, where awardâwinning mixologists like Massimo Zitti craft cuttingâedge cocktails using techniques inspired by chemistryâthink distillation, crystallisation, and even âedible perfumesâ sprayed onto glass rims. The drinks menu is cleverly grouped into Past (classic favourites), Present (timeless cocktails), and Future (experimental creations like fairyâtaleâinspired infusions). Beyond the inventive libations, the bar hosts cocktail masterclasses (e.g., âThe Perfect Serveâ for around ÂŁ35pp) and live blues on Sundays, all framed by decorative touches like antique glassware and quirky taxidermy squirrels. Behind its speakeasy style and scienceâthemed aesthetic lies a space thatâs equal parts mysterious, sophisticated, and warmly welcomingâa perfect spot for aficionados and curious newcomers alike.
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